Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism
Identifieur interne : 000332 ( Main/Exploration ); précédent : 000331; suivant : 000333Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism
Auteurs : Andreas Puschmann [Suède] ; Fabienne C. Fiesel [États-Unis] ; Thomas R. Caulfield [États-Unis] ; Roman Hudec [États-Unis] ; Maya Ando [États-Unis] ; Dominika Truban [États-Unis] ; Xu Hou [États-Unis] ; Kotaro Ogaki [États-Unis] ; Michael G. Heckman [États-Unis] ; Elle D. James [États-Unis] ; Maria Swanberg [Suède] ; Itzia Jimenez-Ferrer [Suède] ; Oskar Hansson [Suède] ; Grzegorz Opala [Pologne] ; Joanna Siuda [Pologne] ; Magdalena Boczarska-Jedynak [Pologne] ; Andrzej Friedman [Pologne] ; Dariusz Koziorowski [Pologne] ; Monika Rudzi Ska-Bar [Pologne] ; Jan O. Aasly [Norvège] ; Timothy Lynch [Irlande (pays)] ; George D. Mellick [Australie] ; Megha Mohan [Australie] ; Peter A. Silburn [Australie] ; Yanosh Sanotsky [Ukraine] ; Carles Vilari O-Güell [États-Unis, Canada] ; Matthew J. Farrer [États-Unis, Canada] ; Li Chen [États-Unis] ; Valina L. Dawson [États-Unis] ; Ted M. Dawson [États-Unis] ; Zbigniew K. Wszolek [États-Unis] ; Owen A. Ross [États-Unis, Irlande (pays)] ; Wolfdieter Springer [États-Unis]Source :
- Brain [ 0006-8950 ] ; 2016.
Abstract
Heterozygous mutations in recessive Parkinson’s disease genes have been postulated to increase disease risk. Puschmann
Url:
DOI: 10.1093/brain/aww261
PubMed: 27807026
PubMed Central: 5379862
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000937
- to stream Pmc, to step Curation: 000937
- to stream Pmc, to step Checkpoint: 000114
- to stream Ncbi, to step Merge: 002134
- to stream Ncbi, to step Curation: 002134
- to stream Ncbi, to step Checkpoint: 002134
- to stream Main, to step Merge: 000333
- to stream Main, to step Curation: 000332
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism</title><author><name sortKey="Puschmann, Andreas" sort="Puschmann, Andreas" uniqKey="Puschmann A" first="Andreas" last="Puschmann">Andreas Puschmann</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF1">1 Lund University, Department of Clinical Sciences Lund, Neurology, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>1 Lund University, Department of Clinical Sciences Lund, Neurology</wicri:regionArea><wicri:noRegion>Neurology</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF2">2 Department of Neurology, Skåne University Hospital, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>2 Department of Neurology, Skåne University Hospital</wicri:regionArea><wicri:noRegion>Skåne University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Fiesel, Fabienne C" sort="Fiesel, Fabienne C" uniqKey="Fiesel F" first="Fabienne C." last="Fiesel">Fabienne C. Fiesel</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Caulfield, Thomas R" sort="Caulfield, Thomas R" uniqKey="Caulfield T" first="Thomas R." last="Caulfield">Thomas R. Caulfield</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Hudec, Roman" sort="Hudec, Roman" uniqKey="Hudec R" first="Roman" last="Hudec">Roman Hudec</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Ando, Maya" sort="Ando, Maya" uniqKey="Ando M" first="Maya" last="Ando">Maya Ando</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Truban, Dominika" sort="Truban, Dominika" uniqKey="Truban D" first="Dominika" last="Truban">Dominika Truban</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Hou, Xu" sort="Hou, Xu" uniqKey="Hou X" first="Xu" last="Hou">Xu Hou</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Ogaki, Kotaro" sort="Ogaki, Kotaro" uniqKey="Ogaki K" first="Kotaro" last="Ogaki">Kotaro Ogaki</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Heckman, Michael G" sort="Heckman, Michael G" uniqKey="Heckman M" first="Michael G." last="Heckman">Michael G. Heckman</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF4">4 Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>4 Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="James, Elle D" sort="James, Elle D" uniqKey="James E" first="Elle D." last="James">Elle D. James</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Swanberg, Maria" sort="Swanberg, Maria" uniqKey="Swanberg M" first="Maria" last="Swanberg">Maria Swanberg</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF5">5 Lund University, Department of Experimental Medical Science, Lund, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>5 Lund University, Department of Experimental Medical Science, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Jimenez Ferrer, Itzia" sort="Jimenez Ferrer, Itzia" uniqKey="Jimenez Ferrer I" first="Itzia" last="Jimenez-Ferrer">Itzia Jimenez-Ferrer</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF5">5 Lund University, Department of Experimental Medical Science, Lund, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>5 Lund University, Department of Experimental Medical Science, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Hansson, Oskar" sort="Hansson, Oskar" uniqKey="Hansson O" first="Oskar" last="Hansson">Oskar Hansson</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF6">6 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>6 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University</wicri:regionArea><wicri:noRegion>Lund University</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF7">7 Memory Clinic, Skåne University Hospital, Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>7 Memory Clinic, Skåne University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Opala, Grzegorz" sort="Opala, Grzegorz" uniqKey="Opala G" first="Grzegorz" last="Opala">Grzegorz Opala</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Siuda, Joanna" sort="Siuda, Joanna" uniqKey="Siuda J" first="Joanna" last="Siuda">Joanna Siuda</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Boczarska Jedynak, Magdalena" sort="Boczarska Jedynak, Magdalena" uniqKey="Boczarska Jedynak M" first="Magdalena" last="Boczarska-Jedynak">Magdalena Boczarska-Jedynak</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Friedman, Andrzej" sort="Friedman, Andrzej" uniqKey="Friedman A" first="Andrzej" last="Friedman">Andrzej Friedman</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF9">9 Department of Neurology, Medical University of Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>9 Department of Neurology, Medical University of Warsaw</wicri:regionArea><wicri:noRegion>Medical University of Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Koziorowski, Dariusz" sort="Koziorowski, Dariusz" uniqKey="Koziorowski D" first="Dariusz" last="Koziorowski">Dariusz Koziorowski</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF9">9 Department of Neurology, Medical University of Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>9 Department of Neurology, Medical University of Warsaw</wicri:regionArea><wicri:noRegion>Medical University of Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Rudzi Ska Bar, Monika" sort="Rudzi Ska Bar, Monika" uniqKey="Rudzi Ska Bar M" first="Monika" last="Rudzi Ska-Bar">Monika Rudzi Ska-Bar</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Aasly, Jan O" sort="Aasly, Jan O" uniqKey="Aasly J" first="Jan O." last="Aasly">Jan O. Aasly</name><affiliation wicri:level="3"><nlm:aff id="aww261-AFF10">10 Department of Neurology, St. Olav’s Hospital, and Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>10 Department of Neurology, St. Olav’s Hospital, and Department of Neuroscience, Norwegian University of Science and Technology, Trondheim</wicri:regionArea><placeName><settlement type="city">Trondheim</settlement><region type="région" nuts="2">Trøndelag</region></placeName></affiliation></author><author><name sortKey="Lynch, Timothy" sort="Lynch, Timothy" uniqKey="Lynch T" first="Timothy" last="Lynch">Timothy Lynch</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF11">11 Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>11 Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Mellick, George D" sort="Mellick, George D" uniqKey="Mellick G" first="George D." last="Mellick">George D. Mellick</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF12">12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Mohan, Megha" sort="Mohan, Megha" uniqKey="Mohan M" first="Megha" last="Mohan">Megha Mohan</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF12">12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Silburn, Peter A" sort="Silburn, Peter A" uniqKey="Silburn P" first="Peter A." last="Silburn">Peter A. Silburn</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF12">12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF13">13 University of Queensland, Asia-Pacific Centre for Neuromodulation, Centre for Clinical Research, Brisbane, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>13 University of Queensland, Asia-Pacific Centre for Neuromodulation, Centre for Clinical Research, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Sanotsky, Yanosh" sort="Sanotsky, Yanosh" uniqKey="Sanotsky Y" first="Yanosh" last="Sanotsky">Yanosh Sanotsky</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF14">14 Lviv Regional Clinical Hospital, Lviv, Ukraine</nlm:aff><country xml:lang="fr">Ukraine</country><wicri:regionArea>14 Lviv Regional Clinical Hospital, Lviv</wicri:regionArea><wicri:noRegion>Lviv</wicri:noRegion></affiliation></author><author><name sortKey="Vilari O Guell, Carles" sort="Vilari O Guell, Carles" uniqKey="Vilari O Guell C" first="Carles" last="Vilari O-Güell">Carles Vilari O-Güell</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF15">15 Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>15 Department of Medical Genetics, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Farrer, Matthew J" sort="Farrer, Matthew J" uniqKey="Farrer M" first="Matthew J." last="Farrer">Matthew J. Farrer</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF15">15 Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>15 Department of Medical Genetics, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Li" sort="Chen, Li" uniqKey="Chen L" first="Li" last="Chen">Li Chen</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF16">16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF17">17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF18">18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685</wicri:regionArea><wicri:noRegion>LA 70130-2685</wicri:noRegion></affiliation></author><author><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF16">16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF17">17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF18">18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685</wicri:regionArea><wicri:noRegion>LA 70130-2685</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF19">19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF20">20 Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>20 Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation></author><author><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF16">16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF17">17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF18">18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685</wicri:regionArea><wicri:noRegion>LA 70130-2685</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF19">19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF21">21 Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>21 Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation></author><author><name sortKey="Wszolek, Zbigniew K" sort="Wszolek, Zbigniew K" uniqKey="Wszolek Z" first="Zbigniew K." last="Wszolek">Zbigniew K. Wszolek</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF22">22 Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>22 Department of Neurology, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Ross, Owen A" sort="Ross, Owen A" uniqKey="Ross O" first="Owen A." last="Ross">Owen A. Ross</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF23">23 School of Medicine and Medical Science, University College Dublin, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>23 School of Medicine and Medical Science, University College Dublin, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF24">24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Springer, Wolfdieter" sort="Springer, Wolfdieter" uniqKey="Springer W" first="Wolfdieter" last="Springer">Wolfdieter Springer</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF24">24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27807026</idno><idno type="pmc">5379862</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379862</idno><idno type="RBID">PMC:5379862</idno><idno type="doi">10.1093/brain/aww261</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000937</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000937</idno><idno type="wicri:Area/Pmc/Curation">000937</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000937</idno><idno type="wicri:Area/Pmc/Checkpoint">000114</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000114</idno><idno type="wicri:Area/Ncbi/Merge">002134</idno><idno type="wicri:Area/Ncbi/Curation">002134</idno><idno type="wicri:Area/Ncbi/Checkpoint">002134</idno><idno type="wicri:doubleKey">0006-8950:2016:Puschmann A:heterozygous:pink:p</idno><idno type="wicri:Area/Main/Merge">000333</idno><idno type="wicri:Area/Main/Curation">000332</idno><idno type="wicri:Area/Main/Exploration">000332</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism</title><author><name sortKey="Puschmann, Andreas" sort="Puschmann, Andreas" uniqKey="Puschmann A" first="Andreas" last="Puschmann">Andreas Puschmann</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF1">1 Lund University, Department of Clinical Sciences Lund, Neurology, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>1 Lund University, Department of Clinical Sciences Lund, Neurology</wicri:regionArea><wicri:noRegion>Neurology</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF2">2 Department of Neurology, Skåne University Hospital, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>2 Department of Neurology, Skåne University Hospital</wicri:regionArea><wicri:noRegion>Skåne University Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Fiesel, Fabienne C" sort="Fiesel, Fabienne C" uniqKey="Fiesel F" first="Fabienne C." last="Fiesel">Fabienne C. Fiesel</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Caulfield, Thomas R" sort="Caulfield, Thomas R" uniqKey="Caulfield T" first="Thomas R." last="Caulfield">Thomas R. Caulfield</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Hudec, Roman" sort="Hudec, Roman" uniqKey="Hudec R" first="Roman" last="Hudec">Roman Hudec</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Ando, Maya" sort="Ando, Maya" uniqKey="Ando M" first="Maya" last="Ando">Maya Ando</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Truban, Dominika" sort="Truban, Dominika" uniqKey="Truban D" first="Dominika" last="Truban">Dominika Truban</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Hou, Xu" sort="Hou, Xu" uniqKey="Hou X" first="Xu" last="Hou">Xu Hou</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Ogaki, Kotaro" sort="Ogaki, Kotaro" uniqKey="Ogaki K" first="Kotaro" last="Ogaki">Kotaro Ogaki</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Heckman, Michael G" sort="Heckman, Michael G" uniqKey="Heckman M" first="Michael G." last="Heckman">Michael G. Heckman</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF4">4 Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>4 Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="James, Elle D" sort="James, Elle D" uniqKey="James E" first="Elle D." last="James">Elle D. James</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Swanberg, Maria" sort="Swanberg, Maria" uniqKey="Swanberg M" first="Maria" last="Swanberg">Maria Swanberg</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF5">5 Lund University, Department of Experimental Medical Science, Lund, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>5 Lund University, Department of Experimental Medical Science, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Jimenez Ferrer, Itzia" sort="Jimenez Ferrer, Itzia" uniqKey="Jimenez Ferrer I" first="Itzia" last="Jimenez-Ferrer">Itzia Jimenez-Ferrer</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF5">5 Lund University, Department of Experimental Medical Science, Lund, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>5 Lund University, Department of Experimental Medical Science, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name sortKey="Hansson, Oskar" sort="Hansson, Oskar" uniqKey="Hansson O" first="Oskar" last="Hansson">Oskar Hansson</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF6">6 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>6 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University</wicri:regionArea><wicri:noRegion>Lund University</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF7">7 Memory Clinic, Skåne University Hospital, Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>7 Memory Clinic, Skåne University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Opala, Grzegorz" sort="Opala, Grzegorz" uniqKey="Opala G" first="Grzegorz" last="Opala">Grzegorz Opala</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Siuda, Joanna" sort="Siuda, Joanna" uniqKey="Siuda J" first="Joanna" last="Siuda">Joanna Siuda</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Boczarska Jedynak, Magdalena" sort="Boczarska Jedynak, Magdalena" uniqKey="Boczarska Jedynak M" first="Magdalena" last="Boczarska-Jedynak">Magdalena Boczarska-Jedynak</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Friedman, Andrzej" sort="Friedman, Andrzej" uniqKey="Friedman A" first="Andrzej" last="Friedman">Andrzej Friedman</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF9">9 Department of Neurology, Medical University of Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>9 Department of Neurology, Medical University of Warsaw</wicri:regionArea><wicri:noRegion>Medical University of Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Koziorowski, Dariusz" sort="Koziorowski, Dariusz" uniqKey="Koziorowski D" first="Dariusz" last="Koziorowski">Dariusz Koziorowski</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF9">9 Department of Neurology, Medical University of Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>9 Department of Neurology, Medical University of Warsaw</wicri:regionArea><wicri:noRegion>Medical University of Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Rudzi Ska Bar, Monika" sort="Rudzi Ska Bar, Monika" uniqKey="Rudzi Ska Bar M" first="Monika" last="Rudzi Ska-Bar">Monika Rudzi Ska-Bar</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF8">8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>8 Department of Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice</wicri:regionArea><wicri:noRegion>Katowice</wicri:noRegion></affiliation></author><author><name sortKey="Aasly, Jan O" sort="Aasly, Jan O" uniqKey="Aasly J" first="Jan O." last="Aasly">Jan O. Aasly</name><affiliation wicri:level="3"><nlm:aff id="aww261-AFF10">10 Department of Neurology, St. Olav’s Hospital, and Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>10 Department of Neurology, St. Olav’s Hospital, and Department of Neuroscience, Norwegian University of Science and Technology, Trondheim</wicri:regionArea><placeName><settlement type="city">Trondheim</settlement><region type="région" nuts="2">Trøndelag</region></placeName></affiliation></author><author><name sortKey="Lynch, Timothy" sort="Lynch, Timothy" uniqKey="Lynch T" first="Timothy" last="Lynch">Timothy Lynch</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF11">11 Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>11 Dublin Neurological Institute at the Mater Misericordiae University Hospital, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Mellick, George D" sort="Mellick, George D" uniqKey="Mellick G" first="George D." last="Mellick">George D. Mellick</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF12">12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Mohan, Megha" sort="Mohan, Megha" uniqKey="Mohan M" first="Megha" last="Mohan">Megha Mohan</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF12">12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Silburn, Peter A" sort="Silburn, Peter A" uniqKey="Silburn P" first="Peter A." last="Silburn">Peter A. Silburn</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF12">12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>12 Eskitis Institute for Drug Discovery, Griffith University, Nathan, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF13">13 University of Queensland, Asia-Pacific Centre for Neuromodulation, Centre for Clinical Research, Brisbane, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>13 University of Queensland, Asia-Pacific Centre for Neuromodulation, Centre for Clinical Research, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Sanotsky, Yanosh" sort="Sanotsky, Yanosh" uniqKey="Sanotsky Y" first="Yanosh" last="Sanotsky">Yanosh Sanotsky</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF14">14 Lviv Regional Clinical Hospital, Lviv, Ukraine</nlm:aff><country xml:lang="fr">Ukraine</country><wicri:regionArea>14 Lviv Regional Clinical Hospital, Lviv</wicri:regionArea><wicri:noRegion>Lviv</wicri:noRegion></affiliation></author><author><name sortKey="Vilari O Guell, Carles" sort="Vilari O Guell, Carles" uniqKey="Vilari O Guell C" first="Carles" last="Vilari O-Güell">Carles Vilari O-Güell</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF15">15 Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>15 Department of Medical Genetics, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Farrer, Matthew J" sort="Farrer, Matthew J" uniqKey="Farrer M" first="Matthew J." last="Farrer">Matthew J. Farrer</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF15">15 Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>15 Department of Medical Genetics, University of British Columbia, Vancouver, BC</wicri:regionArea><wicri:noRegion>BC</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Li" sort="Chen, Li" uniqKey="Chen L" first="Li" last="Chen">Li Chen</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF16">16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF17">17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF18">18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685</wicri:regionArea><wicri:noRegion>LA 70130-2685</wicri:noRegion></affiliation></author><author><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF16">16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF17">17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF18">18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685</wicri:regionArea><wicri:noRegion>LA 70130-2685</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF19">19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF20">20 Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>20 Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation></author><author><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF16">16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>16 Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF17">17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>17 Solomon H Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF18">18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>18 Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130-2685</wicri:regionArea><wicri:noRegion>LA 70130-2685</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF19">19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>19 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF21">21 Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>21 Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205</wicri:regionArea><wicri:noRegion>MD 21205</wicri:noRegion></affiliation></author><author><name sortKey="Wszolek, Zbigniew K" sort="Wszolek, Zbigniew K" uniqKey="Wszolek Z" first="Zbigniew K." last="Wszolek">Zbigniew K. Wszolek</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF22">22 Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>22 Department of Neurology, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Ross, Owen A" sort="Ross, Owen A" uniqKey="Ross O" first="Owen A." last="Ross">Owen A. Ross</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF23">23 School of Medicine and Medical Science, University College Dublin, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>23 School of Medicine and Medical Science, University College Dublin, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF24">24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author><author><name sortKey="Springer, Wolfdieter" sort="Springer, Wolfdieter" uniqKey="Springer W" first="Wolfdieter" last="Springer">Wolfdieter Springer</name><affiliation wicri:level="1"><nlm:aff id="aww261-AFF3">3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>3 Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aww261-AFF24">24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>24 Mayo Graduate School, Neurobiology of Disease, Mayo Clinic, Jacksonville, FL 32224</wicri:regionArea><wicri:noRegion>FL 32224</wicri:noRegion></affiliation></author></analytic><series><title level="j">Brain</title><idno type="ISSN">0006-8950</idno><idno type="eISSN">1460-2156</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold>See Gandhi and Plun-Favreau (doi:<related-article id="d35e428" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/aww320">10.1093/aww320</related-article>) for a scientific commentary on this article</bold>.</p><p>Heterozygous mutations in recessive Parkinson’s disease genes have been postulated to increase disease risk. Puschmann <italic>et al</italic>. report a genetic association between heterozygous PINK1 p.G411S and Parkinson’s disease. They provide structural and functional explanations for a partial dominant-negative effect of the mutant protein, which impairs wild-type PINK1 activity through hetero-dimerization.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Aasly, Jo" uniqKey="Aasly J">JO Aasly</name></author><author><name sortKey="Vilarino Guell, C" uniqKey="Vilarino Guell C">C Vilarino-Guell</name></author><author><name sortKey="Dachsel, Jc" uniqKey="Dachsel J">JC Dachsel</name></author><author><name sortKey="Webber, Pj" uniqKey="Webber P">PJ Webber</name></author><author><name sortKey="West, Ab" uniqKey="West A">AB West</name></author><author><name sortKey="Haugarvoll, K" uniqKey="Haugarvoll K">K Haugarvoll</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abou Sleiman, Pm" uniqKey="Abou Sleiman P">PM Abou-Sleiman</name></author><author><name sortKey="Muqit, Mm" uniqKey="Muqit M">MM Muqit</name></author><author><name sortKey="Mcdonald, Nq" uniqKey="Mcdonald N">NQ McDonald</name></author><author><name sortKey="Yang, Yx" uniqKey="Yang Y">YX Yang</name></author><author><name sortKey="Gandhi, S" uniqKey="Gandhi S">S Gandhi</name></author><author><name sortKey="Healy, Dg" uniqKey="Healy D">DG Healy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aerts, L" uniqKey="Aerts L">L Aerts</name></author><author><name sortKey="Craessaerts, K" uniqKey="Craessaerts K">K Craessaerts</name></author><author><name sortKey="De Strooper, B" uniqKey="De Strooper B">B De Strooper</name></author><author><name sortKey="Morais, Va" uniqKey="Morais V">VA Morais</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Altschul, Sf" uniqKey="Altschul S">SF Altschul</name></author><author><name sortKey="Koonin, Ev" uniqKey="Koonin E">EV Koonin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beilina, A" uniqKey="Beilina A">A Beilina</name></author><author><name sortKey="Van Der Brug, M" uniqKey="Van Der Brug M">M Van Der Brug</name></author><author><name sortKey="Ahmad, R" uniqKey="Ahmad R">R Ahmad</name></author><author><name sortKey="Kesavapany, S" uniqKey="Kesavapany S">S Kesavapany</name></author><author><name sortKey="Miller, Dw" uniqKey="Miller D">DW Miller</name></author><author><name sortKey="Petsko, Ga" uniqKey="Petsko G">GA Petsko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cardona, F" uniqKey="Cardona F">F Cardona</name></author><author><name sortKey="Sanchez Mut, Jv" uniqKey="Sanchez Mut J">JV Sanchez-Mut</name></author><author><name sortKey="Dopazo, H" uniqKey="Dopazo H">H Dopazo</name></author><author><name sortKey="Perez Tur, J" uniqKey="Perez Tur J">J Perez-Tur</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caulfield, T" uniqKey="Caulfield T">T Caulfield</name></author><author><name sortKey="Devkota, B" uniqKey="Devkota B">B Devkota</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caulfield, Tr" uniqKey="Caulfield T">TR Caulfield</name></author><author><name sortKey="Devkota, B" uniqKey="Devkota B">B Devkota</name></author><author><name sortKey="Rollins, Gc" uniqKey="Rollins G">GC Rollins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caulfield, Tr" uniqKey="Caulfield T">TR Caulfield</name></author><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Moussaud Lamodiere, El" uniqKey="Moussaud Lamodiere E">EL Moussaud-Lamodiere</name></author><author><name sortKey="Dourado, Df" uniqKey="Dourado D">DF Dourado</name></author><author><name sortKey="Flores, Sc" uniqKey="Flores S">SC Flores</name></author><author><name sortKey="Springer, W" uniqKey="Springer W">W Springer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caulfield, Tr" uniqKey="Caulfield T">TR Caulfield</name></author><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Springer, W" uniqKey="Springer W">W Springer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coxhead, J" uniqKey="Coxhead J">J Coxhead</name></author><author><name sortKey="Kurzawa Akanbi, M" uniqKey="Kurzawa Akanbi M">M Kurzawa-Akanbi</name></author><author><name sortKey="Hussain, R" uniqKey="Hussain R">R Hussain</name></author><author><name sortKey="Pyle, A" uniqKey="Pyle A">A Pyle</name></author><author><name sortKey="Chinnery, P" uniqKey="Chinnery P">P Chinnery</name></author><author><name sortKey="Hudson, G" uniqKey="Hudson G">G Hudson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Criscuolo, C" uniqKey="Criscuolo C">C Criscuolo</name></author><author><name sortKey="Volpe, G" uniqKey="Volpe G">G Volpe</name></author><author><name sortKey="De Rosa, A" uniqKey="De Rosa A">A De Rosa</name></author><author><name sortKey="Varrone, A" uniqKey="Varrone A">A Varrone</name></author><author><name sortKey="Marongiu, R" uniqKey="Marongiu R">R Marongiu</name></author><author><name sortKey="Mancini, P" uniqKey="Mancini P">P Mancini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eggers, C" uniqKey="Eggers C">C Eggers</name></author><author><name sortKey="Schmidt, A" uniqKey="Schmidt A">A Schmidt</name></author><author><name sortKey="Hagenah, J" uniqKey="Hagenah J">J Hagenah</name></author><author><name sortKey="Bruggemann, N" uniqKey="Bruggemann N">N Bruggemann</name></author><author><name sortKey="Klein, Jc" uniqKey="Klein J">JC Klein</name></author><author><name sortKey="Tadic, V" uniqKey="Tadic V">V Tadic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Ando, M" uniqKey="Ando M">M Ando</name></author><author><name sortKey="Hudec, R" uniqKey="Hudec R">R Hudec</name></author><author><name sortKey="Hill, Ar" uniqKey="Hill A">AR Hill</name></author><author><name sortKey="Castanedes Casey, M" uniqKey="Castanedes Casey M">M Castanedes-Casey</name></author><author><name sortKey="Caulfield, Tr" uniqKey="Caulfield T">TR Caulfield</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Caulfield, Tr" uniqKey="Caulfield T">TR Caulfield</name></author><author><name sortKey="Moussaud Lamodiere, El" uniqKey="Moussaud Lamodiere E">EL Moussaud-Lamodiere</name></author><author><name sortKey="Ogaki, K" uniqKey="Ogaki K">K Ogaki</name></author><author><name sortKey="Dourado, Df" uniqKey="Dourado D">DF Dourado</name></author><author><name sortKey="Flores, Sc" uniqKey="Flores S">SC Flores</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Moussaud Lamodiere, El" uniqKey="Moussaud Lamodiere E">EL Moussaud-Lamodiere</name></author><author><name sortKey="Ando, M" uniqKey="Ando M">M Ando</name></author><author><name sortKey="Springer, W" uniqKey="Springer W">W Springer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Springer, W" uniqKey="Springer W">W Springer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geisler, S" uniqKey="Geisler S">S Geisler</name></author><author><name sortKey="Holmstrom, Km" uniqKey="Holmstrom K">KM Holmstrom</name></author><author><name sortKey="Skujat, D" uniqKey="Skujat D">D Skujat</name></author><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Rothfuss, Oc" uniqKey="Rothfuss O">OC Rothfuss</name></author><author><name sortKey="Kahle, Pj" uniqKey="Kahle P">PJ Kahle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Geisler, S" uniqKey="Geisler S">S Geisler</name></author><author><name sortKey="Holmstrom, Km" uniqKey="Holmstrom K">KM Holmstrom</name></author><author><name sortKey="Treis, A" uniqKey="Treis A">A Treis</name></author><author><name sortKey="Skujat, D" uniqKey="Skujat D">D Skujat</name></author><author><name sortKey="Weber, Ss" uniqKey="Weber S">SS Weber</name></author><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heo, Jm" uniqKey="Heo J">JM Heo</name></author><author><name sortKey="Ordureau, A" uniqKey="Ordureau A">A Ordureau</name></author><author><name sortKey="Paulo, Ja" uniqKey="Paulo J">JA Paulo</name></author><author><name sortKey="Rinehart, J" uniqKey="Rinehart J">J Rinehart</name></author><author><name sortKey="Harper, Jw" uniqKey="Harper J">JW Harper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hooft, Rw" uniqKey="Hooft R">RW Hooft</name></author><author><name sortKey="Sander, C" uniqKey="Sander C">C Sander</name></author><author><name sortKey="Scharf, M" uniqKey="Scharf M">M Scharf</name></author><author><name sortKey="Vriend, G" uniqKey="Vriend G">G Vriend</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hooft, Rw" uniqKey="Hooft R">RW Hooft</name></author><author><name sortKey="Vriend, G" uniqKey="Vriend G">G Vriend</name></author><author><name sortKey="Sander, C" uniqKey="Sander C">C Sander</name></author><author><name sortKey="Abola, Ee" uniqKey="Abola E">EE Abola</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hughes, Aj" uniqKey="Hughes A">AJ Hughes</name></author><author><name sortKey="Daniel, Se" uniqKey="Daniel S">SE Daniel</name></author><author><name sortKey="Kilford, L" uniqKey="Kilford L">L Kilford</name></author><author><name sortKey="Lees, Aj" uniqKey="Lees A">AJ Lees</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ipdg, Consortium" uniqKey="Ipdg C">Consortium IPDG</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jacobson, Mp" uniqKey="Jacobson M">MP Jacobson</name></author><author><name sortKey="Friesner, Ra" uniqKey="Friesner R">RA Friesner</name></author><author><name sortKey="Xiang, Z" uniqKey="Xiang Z">Z Xiang</name></author><author><name sortKey="Honig, B" uniqKey="Honig B">B Honig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, Sm" uniqKey="Jin S">SM Jin</name></author><author><name sortKey="Lazarou, M" uniqKey="Lazarou M">M Lazarou</name></author><author><name sortKey="Wang, C" uniqKey="Wang C">C Wang</name></author><author><name sortKey="Kane, La" uniqKey="Kane L">LA Kane</name></author><author><name sortKey="Narendra, Dp" uniqKey="Narendra D">DP Narendra</name></author><author><name sortKey="Youle, Rj" uniqKey="Youle R">RJ Youle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanes, La" uniqKey="Kanes L">LA Kanes</name></author><author><name sortKey="Lazarou, M" uniqKey="Lazarou M">M Lazarou</name></author><author><name sortKey="Fogel, Ai" uniqKey="Fogel A">AI Fogel</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author><author><name sortKey="Yamano, K" uniqKey="Yamano K">K Yamano</name></author><author><name sortKey="Sarraf, Sa" uniqKey="Sarraf S">SA Sarraf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kazlauskaite, A" uniqKey="Kazlauskaite A">A Kazlauskaite</name></author><author><name sortKey="Kondapalli, C" uniqKey="Kondapalli C">C Kondapalli</name></author><author><name sortKey="Gourlay, R" uniqKey="Gourlay R">R Gourlay</name></author><author><name sortKey="Campbell, Dg" uniqKey="Campbell D">DG Campbell</name></author><author><name sortKey="Ritorto, Ms" uniqKey="Ritorto M">MS Ritorto</name></author><author><name sortKey="Hofmann, K" uniqKey="Hofmann K">K Hofmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kilarski, Ll" uniqKey="Kilarski L">LL Kilarski</name></author><author><name sortKey="Pearson, Jp" uniqKey="Pearson J">JP Pearson</name></author><author><name sortKey="Newsway, V" uniqKey="Newsway V">V Newsway</name></author><author><name sortKey="Majounie, E" uniqKey="Majounie E">E Majounie</name></author><author><name sortKey="Knipe, Md" uniqKey="Knipe M">MD Knipe</name></author><author><name sortKey="Misbahuddin, A" uniqKey="Misbahuddin A">A Misbahuddin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, J" uniqKey="Kim J">J Kim</name></author><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Belmonte, Kc" uniqKey="Belmonte K">KC Belmonte</name></author><author><name sortKey="Hudec, R" uniqKey="Hudec R">R Hudec</name></author><author><name sortKey="Wang, Wx" uniqKey="Wang W">WX Wang</name></author><author><name sortKey="Kim, C" uniqKey="Kim C">C Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="King, Rd" uniqKey="King R">RD King</name></author><author><name sortKey="Sternberg, Mj" uniqKey="Sternberg M">MJ Sternberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klein, C" uniqKey="Klein C">C Klein</name></author><author><name sortKey="Lohmann Hedrich, K" uniqKey="Lohmann Hedrich K">K Lohmann-Hedrich</name></author><author><name sortKey="Rogaeva, E" uniqKey="Rogaeva E">E Rogaeva</name></author><author><name sortKey="Schlossmacher, Mg" uniqKey="Schlossmacher M">MG Schlossmacher</name></author><author><name sortKey="Lang, Ae" uniqKey="Lang A">AE Lang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kondapalli, C" uniqKey="Kondapalli C">C Kondapalli</name></author><author><name sortKey="Kazlauskaite, A" uniqKey="Kazlauskaite A">A Kazlauskaite</name></author><author><name sortKey="Zhang, N" uniqKey="Zhang N">N Zhang</name></author><author><name sortKey="Woodroof, Hi" uniqKey="Woodroof H">HI Woodroof</name></author><author><name sortKey="Campbell, Dg" uniqKey="Campbell D">DG Campbell</name></author><author><name sortKey="Gourlay, R" uniqKey="Gourlay R">R Gourlay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koyano, F" uniqKey="Koyano F">F Koyano</name></author><author><name sortKey="Okatsu, K" uniqKey="Okatsu K">K Okatsu</name></author><author><name sortKey="Kosako, H" uniqKey="Kosako H">H Kosako</name></author><author><name sortKey="Tamura, Y" uniqKey="Tamura Y">Y Tamura</name></author><author><name sortKey="Go, E" uniqKey="Go E">E Go</name></author><author><name sortKey="Kimura, M" uniqKey="Kimura M">M Kimura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krieger, E" uniqKey="Krieger E">E Krieger</name></author><author><name sortKey="Dunbrack, Rl" uniqKey="Dunbrack R">RL Dunbrack</name></author><author><name sortKey="Hooft, Rw" uniqKey="Hooft R">RW Hooft</name></author><author><name sortKey="Krieger, B" uniqKey="Krieger B">B Krieger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krieger, E" uniqKey="Krieger E">E Krieger</name></author><author><name sortKey="Joo, K" uniqKey="Joo K">K Joo</name></author><author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name></author><author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name></author><author><name sortKey="Raman, S" uniqKey="Raman S">S Raman</name></author><author><name sortKey="Thompson, J" uniqKey="Thompson J">J Thompson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name></author><author><name sortKey="Aguirre, Jd" uniqKey="Aguirre J">JD Aguirre</name></author><author><name sortKey="Condos, Te" uniqKey="Condos T">TE Condos</name></author><author><name sortKey="Martinez Torres, Rj" uniqKey="Martinez Torres R">RJ Martinez-Torres</name></author><author><name sortKey="Chaugule, Vk" uniqKey="Chaugule V">VK Chaugule</name></author><author><name sortKey="Toth, R" uniqKey="Toth R">R Toth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lazarou, M" uniqKey="Lazarou M">M Lazarou</name></author><author><name sortKey="Sliter, Da" uniqKey="Sliter D">DA Sliter</name></author><author><name sortKey="Kane, La" uniqKey="Kane L">LA Kane</name></author><author><name sortKey="Sarraf, Sa" uniqKey="Sarraf S">SA Sarraf</name></author><author><name sortKey="Wang, C" uniqKey="Wang C">C Wang</name></author><author><name sortKey="Burman, Jl" uniqKey="Burman J">JL Burman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name></author><author><name sortKey="Vives Bauza, C" uniqKey="Vives Bauza C">C Vives-Bauza</name></author><author><name sortKey="Acin Perez, R" uniqKey="Acin Perez R">R Acin-Perez</name></author><author><name sortKey="Yamamoto, A" uniqKey="Yamamoto A">A Yamamoto</name></author><author><name sortKey="Tan, Y" uniqKey="Tan Y">Y Tan</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marongiu, R" uniqKey="Marongiu R">R Marongiu</name></author><author><name sortKey="Ferraris, A" uniqKey="Ferraris A">A Ferraris</name></author><author><name sortKey="Ialongo, T" uniqKey="Ialongo T">T Ialongo</name></author><author><name sortKey="Michiorri, S" uniqKey="Michiorri S">S Michiorri</name></author><author><name sortKey="Soleti, F" uniqKey="Soleti F">F Soleti</name></author><author><name sortKey="Ferrari, F" uniqKey="Ferrari F">F Ferrari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mellick, Gd" uniqKey="Mellick G">GD Mellick</name></author><author><name sortKey="Siebert, Ga" uniqKey="Siebert G">GA Siebert</name></author><author><name sortKey="Funayama, M" uniqKey="Funayama M">M Funayama</name></author><author><name sortKey="Buchanan, Dd" uniqKey="Buchanan D">DD Buchanan</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author><author><name sortKey="Imamichi, Y" uniqKey="Imamichi Y">Y Imamichi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mills, Rd" uniqKey="Mills R">RD Mills</name></author><author><name sortKey="Sim, Ch" uniqKey="Sim C">CH Sim</name></author><author><name sortKey="Mok, Ss" uniqKey="Mok S">SS Mok</name></author><author><name sortKey="Mulhern, Td" uniqKey="Mulhern T">TD Mulhern</name></author><author><name sortKey="Culvenor, Jg" uniqKey="Culvenor J">JG Culvenor</name></author><author><name sortKey="Cheng, Hc" uniqKey="Cheng H">HC Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mullin, S" uniqKey="Mullin S">S Mullin</name></author><author><name sortKey="Schapira, A" uniqKey="Schapira A">A Schapira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Narendra, Dp" uniqKey="Narendra D">DP Narendra</name></author><author><name sortKey="Jin, Sm" uniqKey="Jin S">SM Jin</name></author><author><name sortKey="Tanaka, A" uniqKey="Tanaka A">A Tanaka</name></author><author><name sortKey="Suen, Df" uniqKey="Suen D">DF Suen</name></author><author><name sortKey="Gautier, Ca" uniqKey="Gautier C">CA Gautier</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okatsu, K" uniqKey="Okatsu K">K Okatsu</name></author><author><name sortKey="Koyano, F" uniqKey="Koyano F">F Koyano</name></author><author><name sortKey="Kimura, M" uniqKey="Kimura M">M Kimura</name></author><author><name sortKey="Kosako, H" uniqKey="Kosako H">H Kosako</name></author><author><name sortKey="Saeki, Y" uniqKey="Saeki Y">Y Saeki</name></author><author><name sortKey="Tanaka, K" uniqKey="Tanaka K">K Tanaka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okatsu, K" uniqKey="Okatsu K">K Okatsu</name></author><author><name sortKey="Oka, T" uniqKey="Oka T">T Oka</name></author><author><name sortKey="Iguchi, M" uniqKey="Iguchi M">M Iguchi</name></author><author><name sortKey="Imamura, K" uniqKey="Imamura K">K Imamura</name></author><author><name sortKey="Kosako, H" uniqKey="Kosako H">H Kosako</name></author><author><name sortKey="Tani, N" uniqKey="Tani N">N Tani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okatsu, K" uniqKey="Okatsu K">K Okatsu</name></author><author><name sortKey="Uno, M" uniqKey="Uno M">M Uno</name></author><author><name sortKey="Koyano, F" uniqKey="Koyano F">F Koyano</name></author><author><name sortKey="Go, E" uniqKey="Go E">E Go</name></author><author><name sortKey="Kimura, M" uniqKey="Kimura M">M Kimura</name></author><author><name sortKey="Oka, T" uniqKey="Oka T">T Oka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ordureau, A" uniqKey="Ordureau A">A Ordureau</name></author><author><name sortKey="Sarraf, Sa" uniqKey="Sarraf S">SA Sarraf</name></author><author><name sortKey="Duda, Dm" uniqKey="Duda D">DM Duda</name></author><author><name sortKey="Heo, Jm" uniqKey="Heo J">JM Heo</name></author><author><name sortKey="Jedrychowski, Mp" uniqKey="Jedrychowski M">MP Jedrychowski</name></author><author><name sortKey="Sviderskiy, Vo" uniqKey="Sviderskiy V">VO Sviderskiy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puschmann, A" uniqKey="Puschmann A">A Puschmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qiu, J" uniqKey="Qiu J">J Qiu</name></author><author><name sortKey="Elber, R" uniqKey="Elber R">R Elber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ricciardi, L" uniqKey="Ricciardi L">L Ricciardi</name></author><author><name sortKey="Petrucci, S" uniqKey="Petrucci S">S Petrucci</name></author><author><name sortKey="Guidubaldi, A" uniqKey="Guidubaldi A">A Guidubaldi</name></author><author><name sortKey="Ialongo, T" uniqKey="Ialongo T">T Ialongo</name></author><author><name sortKey="Serra, L" uniqKey="Serra L">L Serra</name></author><author><name sortKey="Ferraris, A" uniqKey="Ferraris A">A Ferraris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ross, Oa" uniqKey="Ross O">OA Ross</name></author><author><name sortKey="Soto Ortolaza, Ai" uniqKey="Soto Ortolaza A">AI Soto-Ortolaza</name></author><author><name sortKey="Heckman, Mg" uniqKey="Heckman M">MG Heckman</name></author><author><name sortKey="Aasly, Jo" uniqKey="Aasly J">JO Aasly</name></author><author><name sortKey="Abahuni, N" uniqKey="Abahuni N">N Abahuni</name></author><author><name sortKey="Annesi, G" uniqKey="Annesi G">G Annesi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sauve, V" uniqKey="Sauve V">V Sauve</name></author><author><name sortKey="Lilov, A" uniqKey="Lilov A">A Lilov</name></author><author><name sortKey="Seirafi, M" uniqKey="Seirafi M">M Seirafi</name></author><author><name sortKey="Vranas, M" uniqKey="Vranas M">M Vranas</name></author><author><name sortKey="Rasool, S" uniqKey="Rasool S">S Rasool</name></author><author><name sortKey="Kozlov, G" uniqKey="Kozlov G">G Kozlov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shi, G" uniqKey="Shi G">G Shi</name></author><author><name sortKey="Lee, Jr" uniqKey="Lee J">JR Lee</name></author><author><name sortKey="Grimes, Da" uniqKey="Grimes D">DA Grimes</name></author><author><name sortKey="Racacho, L" uniqKey="Racacho L">L Racacho</name></author><author><name sortKey="Ye, D" uniqKey="Ye D">D Ye</name></author><author><name sortKey="Yang, H" uniqKey="Yang H">H Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shiba Fukushima, K" uniqKey="Shiba Fukushima K">K Shiba-Fukushima</name></author><author><name sortKey="Arano, T" uniqKey="Arano T">T Arano</name></author><author><name sortKey="Matsumoto, G" uniqKey="Matsumoto G">G Matsumoto</name></author><author><name sortKey="Inoshita, T" uniqKey="Inoshita T">T Inoshita</name></author><author><name sortKey="Yoshida, S" uniqKey="Yoshida S">S Yoshida</name></author><author><name sortKey="Ishihama, Y" uniqKey="Ishihama Y">Y Ishihama</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shiba Fukushima, K" uniqKey="Shiba Fukushima K">K Shiba-Fukushima</name></author><author><name sortKey="Imai, Y" uniqKey="Imai Y">Y Imai</name></author><author><name sortKey="Yoshida, S" uniqKey="Yoshida S">S Yoshida</name></author><author><name sortKey="Ishihama, Y" uniqKey="Ishihama Y">Y Ishihama</name></author><author><name sortKey="Kanao, T" uniqKey="Kanao T">T Kanao</name></author><author><name sortKey="Sato, S" uniqKey="Sato S">S Sato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sidransky, E" uniqKey="Sidransky E">E Sidransky</name></author><author><name sortKey="Nalls, Ma" uniqKey="Nalls M">MA Nalls</name></author><author><name sortKey="Aasly, Jo" uniqKey="Aasly J">JO Aasly</name></author><author><name sortKey="Aharon Peretz, J" uniqKey="Aharon Peretz J">J Aharon-Peretz</name></author><author><name sortKey="Annesi, G" uniqKey="Annesi G">G Annesi</name></author><author><name sortKey="Barbosa, Er" uniqKey="Barbosa E">ER Barbosa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sim, Ch" uniqKey="Sim C">CH Sim</name></author><author><name sortKey="Gabriel, K" uniqKey="Gabriel K">K Gabriel</name></author><author><name sortKey="Mills, Rd" uniqKey="Mills R">RD Mills</name></author><author><name sortKey="Culvenor, Jg" uniqKey="Culvenor J">JG Culvenor</name></author><author><name sortKey="Cheng, Hc" uniqKey="Cheng H">HC Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siuda, J" uniqKey="Siuda J">J Siuda</name></author><author><name sortKey="Jasinska Myga, B" uniqKey="Jasinska Myga B">B Jasinska-Myga</name></author><author><name sortKey="Boczarska Jedynak, M" uniqKey="Boczarska Jedynak M">M Boczarska-Jedynak</name></author><author><name sortKey="Opala, G" uniqKey="Opala G">G Opala</name></author><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author><author><name sortKey="Moussaud Lamodiere, El" uniqKey="Moussaud Lamodiere E">EL Moussaud-Lamodiere</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Toft, M" uniqKey="Toft M">M Toft</name></author><author><name sortKey="Myhre, R" uniqKey="Myhre R">R Myhre</name></author><author><name sortKey="Pielsticker, L" uniqKey="Pielsticker L">L Pielsticker</name></author><author><name sortKey="White, Lr" uniqKey="White L">LR White</name></author><author><name sortKey="Aasly, Jo" uniqKey="Aasly J">JO Aasly</name></author><author><name sortKey="Farrer, Mj" uniqKey="Farrer M">MJ Farrer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trempe, Jf" uniqKey="Trempe J">JF Trempe</name></author><author><name sortKey="Fon, Ea" uniqKey="Fon E">EA Fon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ward, Cd" uniqKey="Ward C">CD Ward</name></author><author><name sortKey="Gibb, Wr" uniqKey="Gibb W">WR Gibb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wauer, T" uniqKey="Wauer T">T Wauer</name></author><author><name sortKey="Simicek, M" uniqKey="Simicek M">M Simicek</name></author><author><name sortKey="Schubert, A" uniqKey="Schubert A">A Schubert</name></author><author><name sortKey="Komander, D" uniqKey="Komander D">D Komander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wider, C" uniqKey="Wider C">C Wider</name></author><author><name sortKey="Ross, Oa" uniqKey="Ross O">OA Ross</name></author><author><name sortKey="Wszolek, Zk" uniqKey="Wszolek Z">ZK Wszolek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xue, Y" uniqKey="Xue Y">Y Xue</name></author><author><name sortKey="Ouyang, K" uniqKey="Ouyang K">K Ouyang</name></author><author><name sortKey="Huang, J" uniqKey="Huang J">J Huang</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y Zhou</name></author><author><name sortKey="Ouyang, H" uniqKey="Ouyang H">H Ouyang</name></author><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamano, K" uniqKey="Yamano K">K Yamano</name></author><author><name sortKey="Youle, Rj" uniqKey="Youle R">RJ Youle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Yj" uniqKey="Zhang Y">YJ Zhang</name></author><author><name sortKey="Caulfield, T" uniqKey="Caulfield T">T Caulfield</name></author><author><name sortKey="Xu, Yf" uniqKey="Xu Y">YF Xu</name></author><author><name sortKey="Gendron, Tf" uniqKey="Gendron T">TF Gendron</name></author><author><name sortKey="Hubbard, J" uniqKey="Hubbard J">J Hubbard</name></author><author><name sortKey="Stetler, C" uniqKey="Stetler C">C Stetler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Pandit, Sb" uniqKey="Pandit S">SB Pandit</name></author><author><name sortKey="Lee, Sy" uniqKey="Lee S">SY Lee</name></author><author><name sortKey="Borreguero, J" uniqKey="Borreguero J">J Borreguero</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author><author><name sortKey="Wroblewska, L" uniqKey="Wroblewska L">L Wroblewska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Pandit, Sb" uniqKey="Pandit S">SB Pandit</name></author><author><name sortKey="Skolnick, J" uniqKey="Skolnick J">J Skolnick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Skolnick, J" uniqKey="Skolnick J">J Skolnick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Skolnick, J" uniqKey="Skolnick J">J Skolnick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Skolnick, J" uniqKey="Skolnick J">J Skolnick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, H" uniqKey="Zhou H">H Zhou</name></author><author><name sortKey="Skolnick, J" uniqKey="Skolnick J">J Skolnick</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>Canada</li><li>Irlande (pays)</li><li>Norvège</li><li>Pologne</li><li>Suède</li><li>Ukraine</li><li>États-Unis</li></country><region><li>Trøndelag</li></region><settlement><li>Trondheim</li></settlement></list><tree><country name="Suède"><noRegion><name sortKey="Puschmann, Andreas" sort="Puschmann, Andreas" uniqKey="Puschmann A" first="Andreas" last="Puschmann">Andreas Puschmann</name></noRegion><name sortKey="Hansson, Oskar" sort="Hansson, Oskar" uniqKey="Hansson O" first="Oskar" last="Hansson">Oskar Hansson</name><name sortKey="Hansson, Oskar" sort="Hansson, Oskar" uniqKey="Hansson O" first="Oskar" last="Hansson">Oskar Hansson</name><name sortKey="Jimenez Ferrer, Itzia" sort="Jimenez Ferrer, Itzia" uniqKey="Jimenez Ferrer I" first="Itzia" last="Jimenez-Ferrer">Itzia Jimenez-Ferrer</name><name sortKey="Puschmann, Andreas" sort="Puschmann, Andreas" uniqKey="Puschmann A" first="Andreas" last="Puschmann">Andreas Puschmann</name><name sortKey="Swanberg, Maria" sort="Swanberg, Maria" uniqKey="Swanberg M" first="Maria" last="Swanberg">Maria Swanberg</name></country><country name="États-Unis"><noRegion><name sortKey="Fiesel, Fabienne C" sort="Fiesel, Fabienne C" uniqKey="Fiesel F" first="Fabienne C." last="Fiesel">Fabienne C. Fiesel</name></noRegion><name sortKey="Ando, Maya" sort="Ando, Maya" uniqKey="Ando M" first="Maya" last="Ando">Maya Ando</name><name sortKey="Caulfield, Thomas R" sort="Caulfield, Thomas R" uniqKey="Caulfield T" first="Thomas R." last="Caulfield">Thomas R. Caulfield</name><name sortKey="Chen, Li" sort="Chen, Li" uniqKey="Chen L" first="Li" last="Chen">Li Chen</name><name sortKey="Chen, Li" sort="Chen, Li" uniqKey="Chen L" first="Li" last="Chen">Li Chen</name><name sortKey="Chen, Li" sort="Chen, Li" uniqKey="Chen L" first="Li" last="Chen">Li Chen</name><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><name sortKey="Dawson, Ted M" sort="Dawson, Ted M" uniqKey="Dawson T" first="Ted M." last="Dawson">Ted M. Dawson</name><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><name sortKey="Dawson, Valina L" sort="Dawson, Valina L" uniqKey="Dawson V" first="Valina L." last="Dawson">Valina L. Dawson</name><name sortKey="Farrer, Matthew J" sort="Farrer, Matthew J" uniqKey="Farrer M" first="Matthew J." last="Farrer">Matthew J. Farrer</name><name sortKey="Heckman, Michael G" sort="Heckman, Michael G" uniqKey="Heckman M" first="Michael G." last="Heckman">Michael G. Heckman</name><name sortKey="Hou, Xu" sort="Hou, Xu" uniqKey="Hou X" first="Xu" last="Hou">Xu Hou</name><name sortKey="Hudec, Roman" sort="Hudec, Roman" uniqKey="Hudec R" first="Roman" last="Hudec">Roman Hudec</name><name sortKey="James, Elle D" sort="James, Elle D" uniqKey="James E" first="Elle D." last="James">Elle D. James</name><name sortKey="Ogaki, Kotaro" sort="Ogaki, Kotaro" uniqKey="Ogaki K" first="Kotaro" last="Ogaki">Kotaro Ogaki</name><name sortKey="Ross, Owen A" sort="Ross, Owen A" uniqKey="Ross O" first="Owen A." last="Ross">Owen A. Ross</name><name sortKey="Ross, Owen A" sort="Ross, Owen A" uniqKey="Ross O" first="Owen A." last="Ross">Owen A. Ross</name><name sortKey="Springer, Wolfdieter" sort="Springer, Wolfdieter" uniqKey="Springer W" first="Wolfdieter" last="Springer">Wolfdieter Springer</name><name sortKey="Springer, Wolfdieter" sort="Springer, Wolfdieter" uniqKey="Springer W" first="Wolfdieter" last="Springer">Wolfdieter Springer</name><name sortKey="Truban, Dominika" sort="Truban, Dominika" uniqKey="Truban D" first="Dominika" last="Truban">Dominika Truban</name><name sortKey="Vilari O Guell, Carles" sort="Vilari O Guell, Carles" uniqKey="Vilari O Guell C" first="Carles" last="Vilari O-Güell">Carles Vilari O-Güell</name><name sortKey="Wszolek, Zbigniew K" sort="Wszolek, Zbigniew K" uniqKey="Wszolek Z" first="Zbigniew K." last="Wszolek">Zbigniew K. Wszolek</name></country><country name="Pologne"><noRegion><name sortKey="Opala, Grzegorz" sort="Opala, Grzegorz" uniqKey="Opala G" first="Grzegorz" last="Opala">Grzegorz Opala</name></noRegion><name sortKey="Boczarska Jedynak, Magdalena" sort="Boczarska Jedynak, Magdalena" uniqKey="Boczarska Jedynak M" first="Magdalena" last="Boczarska-Jedynak">Magdalena Boczarska-Jedynak</name><name sortKey="Friedman, Andrzej" sort="Friedman, Andrzej" uniqKey="Friedman A" first="Andrzej" last="Friedman">Andrzej Friedman</name><name sortKey="Koziorowski, Dariusz" sort="Koziorowski, Dariusz" uniqKey="Koziorowski D" first="Dariusz" last="Koziorowski">Dariusz Koziorowski</name><name sortKey="Rudzi Ska Bar, Monika" sort="Rudzi Ska Bar, Monika" uniqKey="Rudzi Ska Bar M" first="Monika" last="Rudzi Ska-Bar">Monika Rudzi Ska-Bar</name><name sortKey="Siuda, Joanna" sort="Siuda, Joanna" uniqKey="Siuda J" first="Joanna" last="Siuda">Joanna Siuda</name></country><country name="Norvège"><region name="Trøndelag"><name sortKey="Aasly, Jan O" sort="Aasly, Jan O" uniqKey="Aasly J" first="Jan O." last="Aasly">Jan O. Aasly</name></region></country><country name="Irlande (pays)"><noRegion><name sortKey="Lynch, Timothy" sort="Lynch, Timothy" uniqKey="Lynch T" first="Timothy" last="Lynch">Timothy Lynch</name></noRegion><name sortKey="Ross, Owen A" sort="Ross, Owen A" uniqKey="Ross O" first="Owen A." last="Ross">Owen A. Ross</name></country><country name="Australie"><noRegion><name sortKey="Mellick, George D" sort="Mellick, George D" uniqKey="Mellick G" first="George D." last="Mellick">George D. Mellick</name></noRegion><name sortKey="Mohan, Megha" sort="Mohan, Megha" uniqKey="Mohan M" first="Megha" last="Mohan">Megha Mohan</name><name sortKey="Silburn, Peter A" sort="Silburn, Peter A" uniqKey="Silburn P" first="Peter A." last="Silburn">Peter A. Silburn</name><name sortKey="Silburn, Peter A" sort="Silburn, Peter A" uniqKey="Silburn P" first="Peter A." last="Silburn">Peter A. Silburn</name></country><country name="Ukraine"><noRegion><name sortKey="Sanotsky, Yanosh" sort="Sanotsky, Yanosh" uniqKey="Sanotsky Y" first="Yanosh" last="Sanotsky">Yanosh Sanotsky</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Vilari O Guell, Carles" sort="Vilari O Guell, Carles" uniqKey="Vilari O Guell C" first="Carles" last="Vilari O-Güell">Carles Vilari O-Güell</name></noRegion><name sortKey="Farrer, Matthew J" sort="Farrer, Matthew J" uniqKey="Farrer M" first="Matthew J." last="Farrer">Matthew J. Farrer</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000332 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000332 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:5379862
|texte= Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27807026" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |